Las lesiones tendinosas pueden estar causadas por eventos traumáticos o por cambios degenerativos crónicos, que hacen que el tendón sea más débil y más propenso a las roturas. La curación de las lesiones agudas da lugar a la formación de tejido cicatricial en los tendones, que tienen una resistencia mecánica inferior que los hace susceptibles de volver a lesionarse. Por otra parte, el tratamiento actual de las lesiones crónicas de los tendones (o tendinopatías) es en gran medida paliativo, debido a la comprensión incompleta del trastorno tendinoso.
Presentamos un articulo sobre el uso de Plasma Rico en Plaquetas en las lesiones de ligamentos y tendones de la Prestigiosa Revista Muscle,Ligaments and Tendons Journal por los Doctores Yuan T., Zhang C-Q, Wang
Augmenting tendon and ligament repair with platelet-rich plasma (PRP)

Plasma Rico en Plaquetas en Tendinitis
Contenidos
In vivo clinical and radiological effects of platelet-rich plasma on interstitial supraspinatus lesion: Case series.
Abstract
BACKGROUND: Rotator cuff tear (RCT) is a frequent condition of clinical relevance that can be managed with a symptomatic conservative treatment, but surgery is often needed. Biological components like leukocytes and platelet rich plasma (L-PRP) could represent an alternative curative method for interstitial RCT.

HYPOTHESES: It has been hypothesized that an ultrasound guided L-PRP injection in supraspinatus interstitial RCT could induce radiological healing.
MATERIAL AND METHODS: A prospective case series including 25 patients was performed in order to assess the effect of L-PRP infiltration into supraspinatus interstitial RCTs. Primary outcome was tear size change determined by magnetic resonance imaging arthrogram (MRA) before and 6 months after L-PRP infiltration. Secondary outcomes were Constant score, SANE score, and pain visual analog scale (VAS) after L-PRP infiltration.
RESULTS: Tear volume diminution was statistically significant (P=.007), and a >50% tear volume diminution was observed in 15 patients. A statistically significant improvement of Constant score (P<.001), SANE score (P=.001), and VAS (P<.001) was observed. In 21 patients, Constant score improvement reached the minimal clinical important difference of 10.4 points.
DISCUSSION: We observed a statistically significant and clinically relevant effect on RCT size and clinical parameters after L-PRP infiltration. Such an important improvement of supraspinatus interstitial RCT with conservative management is uncommon, therefore intratendinous L-PRP infiltrations could have been beneficial. This encouraging result could pave the way for future randomized studies in order to formally determinate whether L-PRP infiltrations are a possible alternative to surgical treatment of interstitial RCT.
LEVEL OF EVIDENCE: Prospective observational study; Level of evidence II.
Copyright 2016 Elsevier Masson SAS. All rights reserved.
Caso practico de Plasma Rico en Plaquetas en Tendinosis Rotuliana
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Fecha modificación: 3 Junio 2023